Publikationen

Pilot study for the development of an automatically generated and wearable-based early warning system for the detection of deterioration of hospitalized patients of an acute care hospital
J.J. Reichl, M. Leifke, S. Wehrli, D. Kunz, L. Geissmann, S. Broisch, M. Illien, D. Wellauer, N. von Dach, S. Diener, V. Manser, V. Herren, A. Angerer, S. Hirsch, B. Hölz and J. Eckstein Arch Public Health 82, 179 (2024); https://doi.org/10.1186/s13690-024-01409-y

Determine atrial fibrillation burden with a photoplethysmographic mobile sensor: the atrial fibrillation burden trial: detection and quantification of episodes of atrial fibrillation using a cloud analytics service connected to a wearable with photoplethysmographic sensor
Reissenberger P, Serfözö P, Piper D, Juchler N, Glanzmann S, Gram J, Hensler K, Tonidandel H, Börlin E, D’Souza M, Badertscher P, Eckstein J. European Heart Journal - Digital Health. 2023 Jul; doi.org/10.1093/ehjdh/ztad039

Free-living core body temperature monitoring using a wrist-worn sensor after COVID-19 booster vaccination: a pilot study.
Etienne S, Oliveras R, Schiboni G, Durrer L, Rochat F, Eib P, Zahner M, Osthoff M, Bassetti S, Eckstein J. BioMed Eng OnLine. 2023 Mar;22(1):25. doi: 10.1186/s12938-023-01081-3

Wearable sweat analysis to determine biological age.
Niederberger C, Vermeersch A, Davidhi F, Ewald C, Havenith G, Goldhahn J, Dincer C, Brasier N. Trends in Biotechnology. 2023 Feb 21; doi: 10.1016/j.tibtech.2023.02.001.

Wearable Technologies for Pediatric Patients with Surgical Infections-More than Counting Steps?
Mack I, Juchler N, Rey S, Hirsch S, Hoelz B, Eckstein J, Bielicki J. Biosensors (Basel). 2022 Aug 12;12(8):634. doi: 10.3390/bios12080634. PMID: 36005030

The SMILe integrated care model in allogeneic SteM cell TransplantatIon faciLitated by eHealth: a protocol for a hybrid effectiveness-implementation randomised controlled trial.
De Geest S, Valenta S, Ribaut J, Gerull S, Mielke J, Simon M, Bartakova J, Kaier K, Eckstein J, Leppla L, Teynor A; SMILe team. BMC Health Serv Res. 2022 Aug 20;22(1):1067. doi: 10.1186/s12913-022-08293-8. PMID: 35987671

Comparability of a Blood-Pressure-Monitoring Smartphone Application with Conventional Measurements- A Pilot Study.
Vischer AS, Rosania J, Socrates T, Blaschke C, Eckstein J, Proust YM, Bonnier G, Proença M, Lemay M, Burkard T. Diagnostics (Basel). 2022 Mar 19;12(3):749. doi: 10.3390/diagnostics12030749 PMID: 35328302

A Novel Diagnostic Decision Support System for Medical Professionals: Prospective Feasibility Study.
Timiliotis J, Blümke B, Serfözö PD, Gilbert S, Ondrésik M, Türk E, Hirsch MC, Eckstein J. JMIR Form Res. 2022 Mar 24;6(3):e29943. doi: 10.2196/29943. PMID: 35323125

Perception of physicians and nursing staff members regarding outside versus bedside ward rounds: ancillary analysis of the randomised BEDSIDE-OUTSIDE trial.
Gross S, Beck K, Becker C, Gamp M, Mueller J, Loretz N, Amacher SA, Bohren C, Gaab J, Schuetz P, Mueller B, Fux CA, Leuppi JD, Schaefert R, Langewitz W, Trendelenburg M, Breidthardt T, Eckstein J, Osthoff M, Bassetti S, Hunziker S. Swiss Med Wkly. 2022 Jan 19;152:w30112. doi: 10.4414/smw.2022.w30112. eCollection 2022 Jan 17. PMID: 35072414

Immune thrombocytopenia associated with COVID-19 mRNA vaccine tozinameran - a clinical case and global pharmacovigilance data.
Battegay R, Istampoulouoglou I, Holbro A, Buser A, Hirsiger JR, Eckstein J, Berger CT, Koechlin S, Leuppi-Taegtmeyer AB. Swiss Med Wkly. 2021 Dec 12;151:w30084. doi: 10.4414/smw.2021.w30084. eCollection 2021 Dec 6. PMID: 34908388

Body composition analysis in patients with acute heart failure: the Scale Heart Failure trial.
De Ieso F, Mutke MR, Brasier NK, Raichle CJ, Keller B, Sucker C, Abdelhamid K, Bloch T, Reissenberger P, Schönenberg L, Fischer SK, Saboz J, Weber N, Schädelin S, Bruni N, Wright PR, Eckstein J. ESC Heart Fail. 2021 Dec;8(6):4593-4606. doi: 10.1002/ehf2.13641. Epub 2021 Oct 13. PMID: 34647695

Mobile health solutions for atrial fibrillation detection and management: a systematic review.
Hermans ANL, Gawalko M, Dohmen L, van der Velden RMJ, Betz K, Duncker D, Verhaert DVM, Heidbuchel H, Svennberg E, Neubeck L, Eckstein J, Lane DA, Lip GYH, Crijns HJGM, Sanders P, Hendriks JM, Pluymaekers NAHA, Linz D. Clin Res Cardiol. 2022 May;111(5):479-491. doi: 10.1007/s00392-021-01941-9. Epub 2021 Sep 21. PMID: 34549333

Next-Generation Digital Biomarkers for Tuberculosis and Antibiotic Stewardship: Perspective on Novel Molecular Digital Biomarkers in Sweat, Saliva, and Exhaled Breath.
Brasier N, Osthoff M, De Ieso F, Eckstein J. J Med Internet Res. 2021 Aug 19;23(8):e25907. doi: 10.2196/25907. PMID: 34420925

Effect of Bedside Compared With Outside the Room Patient Case Presentation on Patients' Knowledge About Their Medical Care : A Randomized, Controlled, Multicenter Trial.
Becker C, Gamp M, Schuetz P, Beck K, Vincent A, Hochstrasser S, Metzger K, Widmer M, Thommen E, Mueller B, Fux CA, Leuppi JD, Schaefert R, Langewitz W, Trendelenburg M, Breidthardt T, Eckstein J, Osthoff M, Bassetti S, Hunziker S; BEDSIDE-OUTSIDE Study Group. Ann Intern Med. 2021 Sep;174(9):1282-1292. doi: 10.7326/M21-0909. Epub 2021 Jun 29. PMID: 34181449

The Detection of Vancomycin in Sweat: A Next-Generation Digital Surrogate Marker for Antibiotic Tissue Penetration: A Pilot Study.
Brasier N, Widmer A, Osthoff M, Mutke M, De Ieso F, Brasier-Lutz P, Brown K, Yao L, Broeckling CD, Prenni J, Eckstein J. Digit Biomark. 2021 Jan 14;5(1):24-28. doi: 10.1159/000512947. eCollection 2021 Jan-Apr. PMID: 33615119

iPhone App compared with standard blood pressure measurement -The iPARR trial.
Dörr M, Weber S, Birkemeyer R, Leonardi L, Winterhalder C, Raichle CJ, Brasier N, Burkard T, Eckstein J. Am Heart J. 2021 Mar;233:102-108. doi: 10.1016/j.ahj.2020.12.003. Epub 2020 Dec 13. PMID: 33321118

How should we measure blood pressure? Implications of the fourth blood pressure measurement in office blood pressure.
Vischer AS, Socrates T, Winterhalder C, Eckstein J, Mayr M, Burkard T. J Clin Hypertens (Greenwich). 2021 Jan;23(1):35-43. doi: 10.1111/jch.14130. Epub 2020 Dec 14. PMID: 33319471

Device- and Analytics-Agnostic Infrastructure for Continuous Inpatient Monitoring: A Technical Note.
Brasier N, Geissmann L, Käch M, Mutke M, Hoelz B, De Ieso F, Eckstein J. Digit Biomark. 2020 Aug 20;4(2):62-68. doi: 10.1159/000509279. eCollection 2020 May-Aug. PMID: 33083686

Non-invasive Drug Monitoring of β-Lactam Antibiotics Using Sweat Analysis-A Pilot Study.
Brasier N, Widmer A, Osthoff M, Mutke M, De Ieso F, Brasier-Lutz P, Wolfe L, Aithal V, Broeckling CD, Prenni J, Eckstein J. Front Med (Lausanne). 2020 Aug 25;7:476. doi: 10.3389/fmed.2020.00476. eCollection 2020. PMID: 32984371

Frequency and Predictors of Major Bleeding in Patients With Embolic Strokes of Undetermined Source: NAVIGATE-ESUS Trial.
Mikulík R, Eckstein J, Pearce LA, Mundl H, Rudilosso S, Olavarría VV, Shoamanesh A, Chamorro Á, Martí-Fàbregas J, Veltkamp R, Öztürk Ş, Tatlisumak T, Peacock WF, Berkowitz SD, Connolly SJ, Hart RG. Stroke. 2020 Jul;51(7):2139-2147. doi: 10.1161/STROKEAHA.119.027995. Epub 2020 Jun 10. PMID: 32517582

Comparison and Combination of Single-Lead ECG and Photoplethysmography Algorithms for Wearable- Based Atrial Fibrillation Screening.
Mutke MR, Brasier N, Raichle C, Ravanelli F, Doerr M, Eckstein J. Telemed J E Health. 2021 Mar;27(3):296-302. doi: 10.1089/tmj.2020.0036. Epub 2020 May 18. PMID: 32423358

Sweat as a Source of Next-Generation Digital Biomarkers.
Brasier N, Eckstein J. Digit Biomark. 2019 Dec 5;3(3):155-165. doi: 10.1159/000504387. eCollection 2019 Sep-Dec. PMID: 32095774

Integrative hospital treatment in older patients to benchmark and improve outcome and length of stay - the In-HospiTOOL study.
Kutz A, Koch D, Conca A, Baechli C, Haubitz S, Regez K, Schild U, Caldara Z, Ebrahimi F, Bassetti S, Eckstein J, Beer J, Egloff M, Kaplan V, Ehmann T, Hoess C, Schaad H, Wagner U, de Geest S, Schuetz P, Mueller B. BMC Health Serv Res. 2019 Apr 23;19(1):237. doi: 10.1186/s12913-019-4045-x. PMID: 31014343

Reply: Watch Out: The Many Limitations in Smartwatch-Driven AF Detection.
Dörr M, Nohturfft V, Brasier N, Bosshard E, Djurdjevic A, Gross S, Raichle CJ, Rhinisperger M, Stöckli R, Eckstein J. JACC Clin Electrophysiol. 2019 Apr;5(4):526-527. doi: 10.1016/j.jacep.2019.03.001. PMID: 31000111

Recurrent Stroke With Rivaroxaban Compared With Aspirin According to Predictors of Atrial Fibrillation: Secondary Analysis of the NAVIGATE ESUS Randomized Clinical Trial.
Healey JS, Gladstone DJ, Swaminathan B, Eckstein J, Mundl H, Epstein AE, Haeusler KG, Mikulik R, Kasner SE, Toni D, Arauz A, Ntaios G, Hankey GJ, Perera K, Pagola J, Shuaib A, Lutsep H, Yang X, Uchiyama S, Endres M, Coutts SB, Karlinski M, Czlonkowska A, Molina CA, Santo G, Berkowitz SD, Hart RG, Connolly SJ. JAMA Neurol. 2019 Jul 1;76(7):764-773. doi: 10.1001/jamaneurol.2019.0617. PMID: 30958508

The WATCH AF Trial: SmartWATCHes for Detection of Atrial Fibrillation.
Dörr M, Nohturfft V, Brasier N, Bosshard E, Djurdjevic A, Gross S, Raichle CJ, Rhinisperger M, Stöckli R, Eckstein J. JACC Clin Electrophysiol. 2019 Feb;5(2):199-208. doi: 10.1016/j.jacep.2018.10.006. Epub 2018 Nov 28. PMID: 30784691

Impact of single-visit American versus European office blood pressure measurement procedure on individual blood pressure classification: a cross-sectional study.
Vischer AS, Socrates T, Winterhalder C, Eckstein J, Mayr M, Burkard T. Clin Res Cardiol. 2019 Sep;108(9):990-999. doi: 10.1007/s00392-019-01426-w. Epub 2019 Feb 6. PMID: 30725172

Effect of Na+-channel blockade on the three-dimensional substrate of atrial fibrillation in a model of endo- epicardial dissociation and transmural conduction.
Gharaviri A, Verheule S, Eckstein J, Potse M, Krause R, Auricchio A, Kuijpers NHL, Schotten U. Europace. 2018 Nov 1;20(suppl_3):iii69-iii76. doi: 10.1093/europace/euy236. PMID: 30476060

Impact of Single-Occasion American vs. Canadian Office Blood Pressure Measurement Recommendations on Blood Pressure Classification.
Vischer AS, Mayr M, Socrates T, Winterhalder C, Leonardi L, Eckstein J, Burkard T. Am J Hypertens. 2019 Jan 15;32(2):143-145. doi: 10.1093/ajh/hpy159. PMID: 30371728

Smart mobile devices in health care-smart enough to detect atrial fibrillation?
Eckstein J, Mutke M. J Thorac Dis. 2018 Sep;10(Suppl 26):S3227-S3228. doi: 10.21037/jtd.2018.08.21. PMID: 30370121

Detection of atrial fibrillation with a smartphone camera: first prospective, international, two-centre, clinical validation study (DETECT AF PRO).
Brasier N, Raichle CJ, Dörr M, Becke A, Nohturfft V, Weber S, Bulacher F, Salomon L, Noah T, Birkemeyer R, Eckstein J. Europace. 2019 Jan 1;21(1):41-47. doi: 10.1093/europace/euy176. PMID: 30085018

Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source.
Hart RG, Sharma M, Mundl H, Kasner SE, Bangdiwala SI, Berkowitz SD, Swaminathan B, Lavados P, Wang Y, Wang Y, Davalos A, Shamalov N, Mikulik R, Cunha L, Lindgren A, Arauz A, Lang W, Czlonkowska A, Eckstein J, Gagliardi RJ, Amarenco P, Ameriso SF, Tatlisumak T, Veltkamp R, Hankey GJ, Toni D, Bereczki D, Uchiyama S, Ntaios G, Yoon BW, Brouns R, Endres M, Muir KW, Bornstein N, Ozturk S, O'Donnell MJ, De Vries Basson MM, Pare G, Pater C, Kirsch B, Sheridan P, Peters G, Weitz JI, Peacock WF, Shoamanesh A, Benavente OR, Joyner C, Themeles E, Connolly SJ; NAVIGATE ESUS Investigators. N Engl J Med. 2018 Jun 7;378(23):2191-2201. doi: 10.1056/NEJMoa1802686. Epub 2018 May 16. PMID: 29766772

Performance of a Blood Pressure Smartphone App in Pregnant Women: The iPARR Trial (iPhone App Compared With Standard RR Measurement).
Raichle CJ, Eckstein J, Lapaire O, Leonardi L, Brasier N, Vischer AS, Burkard T. Hypertension. 2018 Jun;71(6):1164-1169. doi: 10.1161/HYPERTENSIONAHA.117.10647. Epub 2018 Apr 9.PMID: 29632098

Reliability of single office blood pressure measurements.
Burkard T, Mayr M, Winterhalder C, Leonardi L, Eckstein J, Vischer AS. Heart. 2018 Jul;104(14):1173-1179. doi: 10.1136/heartjnl-2017-312523. Epub 2018 Mar 12. PMID: 29530989

Characterization of Patients with Embolic Strokes of Undetermined Source in the NAVIGATE ESUS Randomized Trial.
Kasner SE, Lavados P, Sharma M, Wang Y, Wang Y, Dávalos A, Shamalov N, Cunha L, Lindgren A, Mikulik R, Arauz A, Lang W, Czlonkowska A, Eckstein J, Gagliardi R, Amarenco P, Ameriso SF, Tatlisumak T, Veltkamp R, Hankey GJ, Toni DS, Bereczki D, Uchiyama S, Ntaios G, Yoon BW, Brouns R, DeVries Basson MM, Endres M, Muir K, Bornstein N, Ozturk S, O'Donnell M, Mundl H, Pater C, Weitz J, Peacock WF, Swaminathan B, Kirsch B, Berkowitz SD, Peters G, Pare G, Themeles E, Shoamanesh A, Connolly SJ, Hart RG; NAVIGATE ESUS Steering Committee and Investigators. J Stroke Cerebrovasc Dis. 2018 Jun;27(6):1673-1682. doi: 10.1016/j.jstrokecerebrovasdis.2018.01.027. Epub 2018 Mar 7. PMID: 29525076

How disruption of endo-epicardial electrical connections enhances endo-epicardial conduction during atrial fibrillation.
Gharaviri A, Verheule S, Eckstein J, Potse M, Kuklik P, Kuijpers NH, Schotten U. Europace. 2017 Feb 1;19(2):308-318. doi: 10.1093/europace/euv445. PMID: 28175261

Rivaroxaban for secondary stroke prevention in patients with embolic strokes of undetermined source: Design of the NAVIGATE ESUS randomized trial.
Hart RG, Sharma M, Mundl H, Shoamanesh A, Kasner SE, Berkowitz SD, Pare G, Kirsch B, Pogue J, Pater C, Peters G, Davalos A, Lang W, Wang Y, Wang Y, Cunha L, Eckstein J, Tatlisumak T, Shamalov N, Mikulik R, Lavados P, Hankey GJ, Czlonkowska A, Toni D, Ameriso SF, Gagliardi RJ, Amarenco P, Bereczki D, Uchiyama S, Lindgren A, Endres M, Brouns R, Yoon BW, Ntaios G, Veltkamp R, Muir KW, Ozturk S, Arauz A, Bornstein N, Bryer A, O'Donnell MJ, Weitz J, Peacock F, Themeles E, Connolly SJ. Eur Stroke J. 2016 Sep;1(3):146-154. doi: 10.1177/2396987316663049. Epub 2016 Aug 3. PMID: 31008276

Smart detection of atrial fibrillation.
Krivoshei L, Weber S, Burkard T, Maseli A, Brasier N, Kühne M, Conen D, Huebner T, Seeck A, Eckstein J. Europace. 2017 May 1;19(5):753-757. doi: 10.1093/europace/euw125. PMID: 27371660

Validation of a New Heart Rate Measurement Algorithm for Fingertip Recording of Video Signals with Smartphones.
Koenig N, Seeck A, Eckstein J, Mainka A, Huebner T, Voss A, Weber S. Telemed J E Health. 2016 Aug;22(8):631-6. doi: 10.1089/tmj.2015.0212. Epub 2016 Mar 3. PMID: 26938673